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A Comprehensive Guide to 4-MMC and Its Uses

buy mephedrone, commonly referred to as 4-MMC, has gained significant attention in recent years due to its stimulant properties and potential as a recreational drug. Known for its euphoric and stimulating effects, it has become a subject of interest for both users and researchers.

In this article, we’ll explore everything you need to know about buying mephedrone, its effects, legality, uses, and much more.

What is Mephedrone?

Mephedrone, chemically known as 4-methylmethcathinone, is a synthetic stimulant that belongs to the cathinone class. It is structurally related to other substances like amphetamine and MDMA. Mephedrone gained popularity in the mid-2000s due to its euphoric and stimulant effects similar to those of ecstasy and methamphetamine.

Originally sold as a “legal high” in many countries, it became popular in the club scene and among those seeking recreational stimulation. However, as its popularity grew, many nations moved to regulate or ban the sale and distribution of the substance due to concerns over its safety and misuse.

Despite its legal status in various parts of the world, 4-MMC buy and online sales remain an ongoing subject of discussion, and people continue to seek out sources to purchase the substance.

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Why Do People Buy Mephedrone?

The use of 4MMC buy is generally associated with a stimulant and euphoric high, making it a popular choice among individuals looking for an intense and energetic experience. Mephedrone’s effects can vary depending on the dose and individual response, but here are some of the primary reasons why people seek to buy mephedrone:

1. Euphoric Effects

One of the primary reasons people choose to buy 4-MMC is for its euphoric effects. When taken, mephedrone can induce a sense of intense happiness, increased sociability, and heightened sensory perception. This makes it a popular choice in social settings, parties, and festivals.

2. Increased Energy and Stimulation

Mephedrone is known to provide a significant energy boost, making it a favored choice for individuals seeking to stay awake and alert for extended periods. This stimulant effect is often compared to caffeine and other stimulants like amphetamines, but with stronger physical and mental effects.

3. Heightened Sexual Desire

Another common reason individuals use mephedrone is its ability to increase sexual desire and performance. Many users report enhanced libido and a more intense sexual experience when under the influence of 4-MMC.

4. Enhanced Focus and Productivity

Some users also claim that mephedrone helps with focus, concentration, and even productivity. While this effect is typically associated with stimulant substances, it’s important to note that this can come at a cost, as the negative side effects may outweigh the benefits over time.

5. Short Duration of Effects

The effects of mephedrone are usually short-lived, lasting around 2-4 hours, which means users can enjoy the stimulant effects without the long-lasting comedown associated with other substances like methamphetamine or ecstasy.

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How Does 4-MMC Affect the Body?

While mephedrone has its share of users who enjoy its stimulating effects, it’s important to understand the impact it has on the body. Like other stimulants, 4-MMC has a significant effect on the central nervous system (CNS).

1. Dopamine and Serotonin Release

Mephedrone increases the release of dopamine, a neurotransmitter that plays a key role in reward, motivation, and pleasure. It also promotes the release of serotonin, which influences mood, well-being, and happiness. This release of these “feel-good” chemicals explains the euphoric effects associated with mephedrone use.

2. Increased Heart Rate and Blood Pressure

Mephedrone can cause physical effects such as increased heart rate and elevated blood pressure. These effects are common with stimulant substances and may pose a risk to individuals with pre-existing heart conditions. For some users, this can lead to feelings of anxiety, agitation, or discomfort.

3. Dehydration and Hyperthermia

Another side effect of 4-MMC use is dehydration. Like many stimulants, it can increase body temperature and cause users to sweat excessively, leading to potential dehydration. It’s essential to stay hydrated when using mephedrone, especially in hot environments or while engaging in physical activities.

4. Jaw Clenching and Muscle Tension

Many users report experiencing jaw clenching or muscle tension while using 4-MMC, a common side effect of stimulants. This can lead to discomfort and may require the user to take breaks from social activities to alleviate tension.

5. Psychological Effects

Psychologically, mephedrone can cause intense feelings of euphoria, confidence, and social connectedness. However, these positive effects can quickly turn into feelings of anxiety, paranoia, or agitation, especially if taken in high doses. These effects can be heightened if mephedrone is combined with other substances.

Мефедрон

The Russian Term for Mephedrone

The word мефедрон (pronounced “mef-eh-drohn”) is the Russian equivalent of mephedrone. In Russia and other Eastern European countries, мефедрон is commonly used to refer to the drug, and it has become quite popular due to its availability on the black market.

While мефедрон is illegal in many countries, its legal status may vary depending on the region. In some places, 4-MMC or мефедрон is still sold openly, albeit with increasing regulation. If you are in a region where мефедрон is legal or decriminalized, you may find it easier to buy the substance. However, it’s essential to be aware of potential risks and legal issues that may arise from purchasing this substance.

Legal Status: Can You Buy Mephedrone?

Before considering a 4-MMC buy, it’s essential to understand the legal status of mephedrone in your country. The legal landscape for 4-MMC has changed significantly since it was first sold as a legal high. Many countries have moved to ban its sale, production, and distribution due to concerns over its safety and potential for abuse.

1. Countries Where Mephedrone Is Banned

In many countries, including the United States, the United Kingdom, Canada, Australia, and parts of Europe, mephedrone is classified as a controlled substance. This means that it is illegal to buy, sell, or possess 4-MMC in these regions. Enforcement of these laws can vary, but purchasing mephedrone in these areas can result in legal consequences.

2. Countries with Less Regulation

There are still some regions where mephedrone remains legal or is lightly regulated. In certain parts of Eastern Europe, Russia, and Asia, мефедрон can be found in markets with less government oversight. However, even in these regions, the laws surrounding its production and sale may change rapidly.

3. Online Purchases and Risks

In the age of the internet, purchasing 4-MMC online has become a common method of acquiring mephedrone. However, this comes with significant risks. Many websites that sell 4-MMC are operating illegally, and there is always a chance that the product may be contaminated or counterfeit.

For users considering purchasing mephedrone online, it’s crucial to conduct thorough research on the vendor, read reviews, and ensure that the product is lab-tested for purity and quality. Even then, buying 4-MMC online poses significant risks of legal issues, fraud, or purchasing dangerous substances.

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How to Safely Use Mephedrone

While mephedrone can offer an enjoyable and stimulating experience, it’s important to use it responsibly to minimize potential risks. Here are some tips for using 4MMC buy safely:

1. Start with Low Dosages

If you are new to mephedrone, it’s essential to start with a low dose and assess your body’s reaction. This will help you gauge your tolerance and minimize the risk of adverse effects.

2. Stay Hydrated

As mephedrone can lead to dehydration, it’s important to drink water throughout the experience. However, avoid drinking excessive amounts of water at once, as this can also lead to negative effects like water intoxication.

3. Use in a Safe Environment

Using mephedrone in a safe, comfortable setting with trusted individuals can help minimize the risk of anxiety or negative psychological effects. Having a designated “trip sitter” who can help guide the experience may also provide additional safety.

4. Avoid Combining with Other Substances

Combining mephedrone with other stimulants or substances, such as alcohol or other drugs, can amplify negative side effects and increase the risk of harm. It’s best to avoid mixing substances while using 4-MMC.

Conclusion: Is Buying Mephedrone Worth It?

If you are considering a 4-MMC buy, it’s essential to weigh the potential benefits against the risks. Mephedrone offers powerful stimulant effects that can enhance social experiences and boost energy, but it also carries significant risks, including legal issues, physical side effects, and psychological harm.

As with any substance, it is important to approach mephedrone responsibly, start with small doses, stay hydrated, and use it in a safe environment. Whether you’re considering 4-MMC buy for recreational purposes or curious about its effects, understanding the substance, its risks, and its legal status will help you make an informed decision.

Ultimately, the decision to use mephedrone should not be taken lightly. Ensure that you are aware of the laws in your region, understand the potential side effects, and consider the impact on your health and well-being before making a purchase.

How to Purchase 4-MMC Safely

For those who have made the decision to buy 4-MMC, it is crucial to consider safety at every step of the process. Purchasing mephedrone comes with inherent risks, particularly when done online, given the potential for scams, counterfeit products, and legal ramifications. Here are several essential tips on how to buy 4-MMC safely:

1. Research the Vendor Carefully

When purchasing 4-MMC online, always start by researching the vendor thoroughly. Look for reputable sellers that have positive customer reviews, clear contact information, and a transparent history of operations. Be wary of unverified sites that might offer low prices but lack reliable customer service or product guarantees.

Customer reviews: Look for websites with numerous, well-detailed reviews from previous buyers. Reviews should include information about shipping times, product quality, and the effectiveness of customer support.

Product quality: Make sure that the product being sold is lab-tested for purity. Reliable sellers often provide lab results, showing the authenticity and safety of their mephedrone.

2. Check for Discreet Shipping

Given the legal status of 4-MMC in many regions, it’s important to choose a vendor that offers discreet shipping. Reputable sellers typically ship their products in plain, unmarked packaging to ensure privacy and avoid detection.

3. Understand the Legal Risks

Before making a purchase, understand the legal risks associated with buying 4-MMC in your country or region. Even if the substance is legal in certain areas, enforcement of laws can vary, and purchasing from an unregulated source could expose you to legal action.

Research the current legal status of 4-MMC in your location and make an informed decision based on the potential consequences.

4. Look for Secure Payment Methods

For added safety, choose vendors who offer secure payment methods, such as cryptocurrencies or other privacy-focused payment options. Avoid vendors that ask for unsecured or unconventional forms of payment, as this could be a sign of a scam.

How to Use Mephedrone Responsibly

While 4-MMC has a reputation for providing an exciting, stimulating experience, it’s crucial to recognize the importance of responsible use. To ensure safety, it’s essential to follow specific guidelines when using mephedrone:

1. Understand Your Body’s Limits

It’s important to recognize your body’s tolerance when using any stimulant. Mephedrone is powerful and can be overwhelming at higher doses, especially for those who are new to stimulants. Start with a small dose to gauge your body’s response, and avoid escalating the dose quickly.

2. Create a Comfortable Setting

Your physical and mental environment plays a critical role in how your experience with 4-MMC will unfold. For the most positive effects, use mephedrone in a safe, relaxed setting where you feel comfortable and are surrounded by trusted friends. A familiar, calm environment can help reduce the chances of negative psychological reactions, such as anxiety or panic.

3. Never Use Alone

Using 4-MMC with a trusted companion, commonly referred to as a “trip sitter,” can provide an added layer of safety. A trip sitter can assist if you experience any discomfort or overwhelming feelings during the high. They can also help ensure that you’re hydrated and supported emotionally during your experience.

4. Take Regular Breaks

Because 4-MMC can increase your energy levels, it’s easy to become caught up in a fast-paced, non-stop high. However, taking breaks between doses or engaging in relaxing activities can help mitigate the risk of overstimulation or physical discomfort.

5. Avoid Mixing with Other Substances

Avoid mixing 4-MMC with other substances, especially alcohol or other stimulants. This can increase the strain on your body, leading to higher risks of side effects, including dehydration, anxiety, heart problems, and excessive stimulation. Always be cautious when combining substances, and avoid poly-drug use unless you are fully aware of the risks involved.

The Risks of Mephedrone Use

While mephedrone offers euphoria and energy, it’s important to be aware of the risks associated with its use. Like many stimulants, it can cause several negative side effects, especially when used irresponsibly or in high doses.

1. Psychological Risks

The most common psychological effects associated with 4-MMC include:

• Anxiety: Some individuals may experience anxiety, especially if they are using 4-MMC in high doses or in an uncomfortable setting.
• Paranoia: In certain cases, users may feel paranoid or detached from reality, particularly with frequent or high-dose use.
• Mood swings: As the stimulant effects wear off, users may experience mood swings, irritability, or feelings of depression.
• Dependence: Regular use of mephedrone may increase the likelihood of psychological dependence. Users may find themselves seeking the substance to recreate the feelings of euphoria and energy.

2. Physical Side Effects

Common physical side effects of mephedrone include:

Increased heart rate and blood pressure: As a stimulant, 4-MMC can elevate your heart rate and blood pressure, which may be dangerous for those with pre-existing cardiovascular conditions.

Dehydration: Mephedrone can lead to dehydration, especially if used in warm environments or while engaging in physical activity.

Teeth grinding and jaw clenching: This is a common side effect of many stimulant drugs, including mephedrone. It can cause discomfort, and prolonged use may result in dental issues.

Sleep disturbances: As 4-MMC is a stimulant, it can cause difficulty sleeping, especially if taken later in the day.

3. Long-Term Effects

Chronic or long-term use of mephedrone may result in more severe side effects, including:

• Cognitive impairment: Prolonged use of 4-MMC may have an impact on cognitive function, including memory, concentration, and decision-making.
• Heart issues: Chronic stimulant use can contribute to cardiovascular problems, such as arrhythmias, and may increase the risk of heart attack or stroke.

Conclusion: Should You Buy Mephedrone?

The decision to buy 4-MMC or mephedrone should not be taken lightly. While it can provide an intense, euphoric experience, there are significant risks involved, particularly with regular or heavy use. It’s crucial to consider the legal implications, health risks, and potential psychological effects before purchasing 4-MMC.

If you choose to buy mephedrone, ensure that you are sourcing it from a reputable vendor, using it responsibly, and taking proper precautions. Starting with a low dose, staying hydrated, and having a trusted friend with you can help mitigate the risks associated with its use.

Ultimately, 4-MMC is not a substance to be taken lightly. If used cautiously and in moderation, it can offer a brief but intense experience. However, frequent use can lead to dangerous consequences, both mentally and physically. Always be mindful of the risks, and ensure that you make informed decisions when it comes to buying mephedrone.

FAQ: Frequently Asked Questions About Mephedrone

1. What is Mephedrone (4-MMC)?

Mephedrone, also known as 4-methylmethcathinone (4-MMC), is a synthetic stimulant that belongs to the cathinone class. It produces effects similar to amphetamines, providing stimulation, euphoria, and increased sociability.

It has been used recreationally in party settings but has also been banned or regulated in many countries due to its potential for abuse and adverse health effects.

2. Is Mephedrone Legal?

The legality of 4-MMC varies by country and region. In many places, including the United States, the United Kingdom, and much of Europe, mephedrone has been classified as a controlled substance, making it illegal to buy, sell, or possess.

However, in some regions, it may still be available in the black market or legal gray areas. Always check local laws before attempting to buy mephedrone.

3. What Are the Effects of Mephedrone?

Mephedrone induces stimulant effects, including:

• Euphoria and heightened sociability
• Increased energy and focus
• Elevated heart rate and blood pressure
• Enhanced libido and sexual experience
• Jaw clenching and muscle tension

However, it can also cause negative effects like anxiety, paranoia, and dehydration, especially at high doses.

4. How Long Do the Effects of Mephedrone Last?

The effects of mephedrone typically last for about 2-4 hours. The initial euphoria is followed by a comedown period, where users may experience feelings of irritability, depression, or fatigue. The short duration of effects often leads users to take more, which can increase the risks of adverse effects.

5. Is Mephedrone Addictive?

While 4-MMC is not as physically addictive as substances like heroin or cocaine, it can lead to psychological dependence. Some users may develop a craving for the euphoric effects and use it repeatedly, which could result in tolerance and an increased risk of negative health outcomes.

6. How Can I Safely Use Mephedrone?

To use mephedrone safely, follow these guidelines:

• Start with a low dose to assess your tolerance.
• Stay hydrated but avoid excessive water consumption.
• Use in a comfortable, safe setting with trusted people.
• Avoid mixing with other substances, especially alcohol or other stimulants.
• Take breaks and avoid prolonged use to minimize strain on your body.

7. What Are the Risks of Using Mephedrone?

Some of the risks associated with using mephedrone include:

• Increased heart rate and blood pressure
• Dehydration and overheating
• Anxiety, paranoia, or mood swings
• Jaw clenching and muscle tension
• Cognitive impairment and long-term psychological effects

8. Can Mephedrone Be Detected on a Drug Test?

Yes, 4-MMC can be detected on drug tests, although it might not show up on standard drug screens. Specialized tests designed to detect synthetic cathinones, including mephedrone, can identify its presence in urine, blood, or saliva samples.

People Also Ask: Common Queries About Mephedrone

1. Where Can I Buy Mephedrone (4-MMC)?

Mephedrone can be found through certain online vendors, although the legality and safety of these transactions vary by region. In many places, 4-MMC is illegal, so purchasing it online could expose you to legal risks. Always ensure that you are aware of local laws and use reputable vendors if you decide to purchase mephedrone.

2. What Does Mephedrone Do to Your Brain?

Mephedrone affects the brain by increasing the release of dopamine and serotonin, neurotransmitters responsible for feelings of pleasure and happiness. These effects result in euphoria, increased energy, and enhanced sociability. However, excessive use of 4-MMC can lead to psychological dependence, cognitive impairment, and other long-term consequences.

3. Is Mephedrone Dangerous?

Mephedrone can be dangerous when used irresponsibly or in excessive amounts. It can cause serious side effects such as elevated heart rate, high blood pressure, anxiety, dehydration, and potential overdose. Long-term use increases the risk of dependence and adverse psychological effects.

4. How Do I Know if Mephedrone Is Safe?

The safest way to use 4-MMC is to purchase it from a reputable source that tests the product for purity and quality. Additionally, it’s essential to use it in moderation, start with a low dose, and always follow harm-reduction practices. Be mindful of the risks and educate yourself on safe use to avoid dangerous outcomes.

5. What Are the Alternatives to Mephedrone?

If you’re looking for a legal alternative to mephedrone, consider substances like caffeine or kava for energy and relaxation, respectively. For those seeking a euphoric, social high, consider MDMA or mushrooms (psilocybin), which offer similar effects but carry their own risks. Always weigh the potential risks and effects of any substance before use.

Related Searches and Topics with Answers

1. Buy 4-MMC Online

Answer: Purchasing 4-MMC online can be done through various vendors, but it’s crucial to understand the legal implications and risks involved. In many regions, mephedrone is illegal, and buying it online can expose you to scams, counterfeit products, and legal trouble.

If you choose to buy online, always research reputable vendors, ensure the product is lab-tested, and use secure payment methods. Be sure to comply with local laws.

2. Mephedrone Legal Status

Answer: The legal status of 4-MMC varies widely across different countries. In many nations, including the United States, the United Kingdom, and much of Europe, mephedrone is classified as a controlled substance, making it illegal to buy, sell, or possess.

However, in some areas, it may be less regulated or still legal for research purposes. Always check your country’s specific drug laws to determine whether 4-MMC is allowed where you live.

3. Mephedrone Effects and Risks

Answer: The effects of mephedrone are similar to those of other stimulants like amphetamines or ecstasy. These include euphoria, heightened energy, increased sociability, and enhanced focus. However, risks include dehydration, anxiety, elevated heart rate, and long-term cognitive impairment.

There is also the potential for psychological dependence. It’s important to be aware of the short- and long-term effects when considering using 4-MMC.

4. Mephedrone vs. MDMA

Answer: Both mephedrone and MDMA are synthetic stimulants that provide similar euphoric and stimulating effects, but they differ chemically and in their duration of action. MDMA (Ecstasy) primarily boosts serotonin levels, producing intense feelings of well-being and emotional closeness.

Mephedrone, on the other hand, increases dopamine, serotonin, and norepinephrine levels, leading to more stimulating and energizing effects. However, both carry risks such as dehydration, anxiety, and, in some cases, serotonin syndrome.

5. 4-MMC for Sale

Answer: Purchasing 4-MMC for sale is common through both online and black-market vendors. However, it’s essential to be cautious when searching for mephedrone for sale, as many of these vendors may not provide pure, unadulterated products. Ensure you’re purchasing from a reputable source that offers lab-tested products.

Remember, buying 4-MMC may be illegal in your area, and there could be legal consequences if caught.

6. Synthetic Cathinones

Answer: Synthetic cathinones are a class of drugs that include substances like mephedrone, methcathinone, and others that are chemically related to amphetamines. These substances have stimulant effects similar to those of cocaine or methamphetamine.

Many synthetic cathinones are marketed as “bath salts” or “legal highs,” but they are associated with significant risks, including severe psychological effects, addiction, and physical harm. Understanding the full scope of synthetic cathinones is essential before considering their use.

7. Stimulant Drugs Like Mephedrone

Answer: Mephedrone belongs to the stimulant class of drugs, which includes substances like amphetamine, cocaine, and MDMA. Stimulants are known to increase alertness, energy, and focus, but they can also cause dangerous side effects such as increased heart rate, high blood pressure, and anxiety.

Other stimulant drugs, such as methamphetamine, carry even greater risks of addiction and physical harm, so understanding their properties and risks is important.

8. Mephedrone Addiction

Answer: Mephedrone addiction is possible due to the drug’s stimulating and euphoric effects. While 4-MMC is not physically addictive like substances such as alcohol or opioids, it can cause psychological dependence.

Frequent use of mephedrone may lead to cravings, tolerance (requiring higher doses to achieve the same effects), and negative psychological outcomes, such as anxiety or depression. If you suspect you or someone you know may be struggling with addiction, seeking professional help is essential.

9. How to Safely Use Stimulants

Answer: Using stimulants, including 4-MMC, requires caution. If you choose to use mephedrone, here are some harm-reduction practices:

• Start with a low dose to understand your tolerance.
• Stay hydrated but avoid over-drinking water.
• Use in a safe, familiar environment with friends you trust.
• Avoid combining with other substances, especially alcohol or other stimulants.
• Take regular breaks and give your body time to rest.

It’s also important to consider the psychological effects of stimulants, which can include anxiety, agitation, or paranoia, especially at higher doses.

10. Alternative Legal Highs to Mephedrone

Answer: If you’re seeking legal highs or alternatives to mephedrone, some options are available in certain regions where 4-MMC is banned. Legal alternatives may include:

• Kava: A non-stimulant herb known for its calming and sedative properties.
• Kraken: A strain of kratom that can provide stimulation or relaxation, depending on the dosage.
• Caffeine: A mild stimulant found in coffee and energy drinks, often used for a quick boost in energy and alertness.
• CBD (Cannabidiol): While not a stimulant, CBD may promote relaxation and reduce anxiety in some individuals.

Remember that “legal highs” can have varying effects, and it’s essential to research their safety and legality in your area.

Conclusion: Understanding Mephedrone and Its Alternatives

If you’re considering buying mephedrone (4-MMC), it’s essential to understand the potential risks and effects, as well as the legal implications in your region. While 4-MMC may offer a stimulating and euphoric experience, it can also lead to harmful side effects, addiction, and psychological issues if used irresponsibly.

Ensure that you are purchasing from reputable sources, using the substance safely, and taking all precautions necessary. If you’re looking for alternatives to 4-MMC, substances like kava, kratom, or CBD can provide different effects and are often legally available in many areas.

Whatever choice you make, always prioritize your health, safety, and well-being when experimenting with any psychoactive substance.

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Mephedrone, also known as 4-methylmethcathinone, 4-MMC, and 4-methylephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include drone,M-CAT,White Magic, and meow meow.

It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. It comes in the form of tablets or crystals, which users can swallow, snort or inject, producing effects similar to those of MDMA, amphetamines and cocaine.

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In addition to its stimulant effects, mephedrone produces side effects, of which bruxism is the most common. The metabolism of mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage.

Mephedrone was first synthesised in 1929 but did not become widely known until it was rediscovered in 1999–2000 at which point it was legal to produce and possess in many countries.

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By 2000, mephedrone was reported to be available for sale on the internet, by 2008 law enforcement agencies had become aware of the compound, and by 2010, it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom.

Mephedrone was first made illegal in Israel in 2008, followed by Sweden later that year. This classification was made permanent in July 2012 with the passage of the Synthetic Drug Abuse Prevention Act (SDAPA).

Recreational

Users have reported that mephedrone causes euphoria, stimulation, an enhanced appreciation for music, an elevated mood, decreased hostility, improved mental function and mild sexual stimulation; these effects are similar to the effects of cocaine, amphetamines and MDMA, and last different amounts of time depending on the way the drug is taken.

Available forms

Mephedrone can come in the form of capsules, tablets or white powder that users may swallow, snort, inject, smoke or use rectally. When taken orally, users reported they could feel the effects within 15–45 minutes; when snorted, the effects were felt within minutes and peaked within half an hour. Buy crystal meth online

Purity

One published study that analysed samples of mephedrone bought using the internet in the UK in 2010 found it was racemic (a mixture of both stereoisomers) and of high purity.An unpublished study of six samples also ordered off the internet in the UK in 2010 found they contained very few organic impurities.

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When snorted, it can also cause nose bleeds and nose burns.

A survey conducted by the UK National Addiction Centre found 67% of mephedrone users experienced sweating, 51% suffered from headaches, 43% from heart palpitations, 27% from nausea and 15% from cold or blue fingers,indicative of vasoconstriction occurring.

three required treatment with benzodiazepines, predominantly to control their agitation. They reported none of their patients suffered from cold or blue peripheries, contrary to other reports.

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Nine of the 15 of patients had a Glasgow coma scale (GCS) of 15, indicating they were in a normal mental state, four had a GCS below 8, but these patients all reported using a central nervous system depressant, most commonly GHB, with mephedrone. The patients also reported polydrug use of a variety of compounds.

Neurotoxicity

Neurotoxic effect of mephedrone on serotonin (5-HT) and dopamine (DA) systems remains controversial. Although some studies in animal models reported no damage to DA nerve endings in the striatum and no significant changes in brain monoamine levels, some others suggested a rapid reduction in 5-HT and DA transporter function.

Reinforcement disorders

There have been reports of users craving mephedrone, suggesting it may be addictive.

Overdose – Toxicity

In 2009, one case of sympathomimetic toxicity was reported in the UK after a person took 0.2 g of mephedrone orally, and after this did not achieve the desired effect, subcutaneously injected 3.8 g mixed with water into his thighs.

Simon Gibbons and Mire Zloh of the School of Pharmacy, University of London stated, based on the chemical similarities between methcathinone and mephedrone, “it is highly likely that mephedrone will display neurotoxicity”.

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Doctors who treated a 15-year-old female suffering from mephedrone intoxication suggested in The Lancet that, like MDMA, mephedrone may promote serotonin-mediated release of antidiuretic hormone, resulting in hyponatraemia and an altered mental state.

Meow meow

One case of acquired methaemoglobinaemia, where a patient had “bluish lips and fingers”, has also been reported, after the user snorted one gram of mephedrone. The patient started to recover after arriving at the hospital and it was not necessary to administer any medication.

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Mephedrone Information Mephedrone, or dimethylmethcathinone, 1-(4-methylphenyl)- 2-methylaminopropan-1-one, is currently accessible to have in the UK, USA, Australia and beyong. Elective names were Mcat, 4-MMC, MM-Cat , Meow, or 4-methylmethcathinone.

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